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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
28.18
Human Site:
T281
Identified Species:
47.69
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
T281
E
S
A
S
H
N
E
T
Y
R
R
I
V
K
V
Chimpanzee
Pan troglodytes
XP_511856
395
44529
T332
E
S
A
S
H
N
E
T
Y
R
R
I
V
K
V
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
T499
E
S
A
S
H
N
E
T
Y
R
R
I
V
K
V
Dog
Lupus familis
XP_849906
346
39574
T283
E
S
A
S
H
N
E
T
Y
R
R
I
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
F278
L
M
V
G
N
P
P
F
E
S
P
S
H
S
E
Rat
Rattus norvegicus
O55099
343
39216
F276
L
M
V
G
N
P
P
F
E
S
P
S
H
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
T236
E
A
E
T
Y
Q
E
T
Y
R
S
I
S
K
V
Chicken
Gallus gallus
XP_425725
409
46456
F343
F
L
V
G
K
P
P
F
E
A
Q
T
Y
Q
E
Frog
Xenopus laevis
Q6DE08
361
41717
T297
D
S
P
S
H
T
E
T
H
R
R
I
V
N
V
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
T257
E
T
A
S
H
A
E
T
Y
K
R
I
T
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
T259
E
S
N
S
T
E
S
T
Y
S
K
I
R
R
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
F243
A
A
I
K
A
A
R
F
T
Y
P
D
S
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
S232
P
F
E
A
M
E
H
S
D
T
Y
R
R
I
V
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
E304
G
A
P
P
F
E
E
E
M
K
D
T
T
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
53.3
0
66.6
73.3
N.A.
40
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
73.3
13.3
80
86.6
N.A.
60
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
36
8
8
15
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% D
% Glu:
50
0
15
0
0
22
58
8
22
0
0
0
0
0
22
% E
% Phe:
8
8
0
0
8
0
0
29
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
43
0
8
0
8
0
0
0
15
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
58
0
8
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
15
8
0
0
43
15
% K
% Leu:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
15
0
0
8
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
15
29
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
15
8
0
22
22
0
0
0
22
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
43
43
8
15
8
0
% R
% Ser:
0
43
0
50
0
0
8
8
0
22
8
15
15
15
0
% S
% Thr:
0
8
0
8
8
8
0
58
8
8
0
15
15
0
0
% T
% Val:
0
0
22
0
0
0
0
0
0
0
0
0
36
8
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
50
8
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _